Aseptic separator for biopharma applications
Achieve high purity for your pharmaceutical liquids with a centrifuge that ensures gentle handling and low shear in aseptic processing, making it ideal for maintaining the integrity of sensitive biologic formulations.
The GEA Pharma Separator Aseptic C is engineered for precision separation and clarification of liquid biopharmaceuticals. Utilizing a unique hydrohermetic inlet, it ensures gentle product handling to protect shear-sensitive cells and proteins. Designed for processes involving monoclonal antibodies and vaccine suspensions, it offers an optimized bowl design for different solid content levels. Automation is smooth with ASME BPE compliance, automatic SIP, and CIP features, ensuring high cleanability and validation ease. Capable of continuous operation, it integrates seamlessly into existing lines with its plug-and-produce skid design, featuring four bowl sizes to match processing needs. The GEA Integrated Direct Drive reduces emissions in cleanroom environments and lessens maintenance due to fewer wear parts, promoting longevity and efficiency.
Benefits
- Ensures high product purity through gentle, controlled separation processes.
- Enhances operational efficiency with continuous, automated cleaning cycles.
- Integrates effortlessly into existing production lines with flexible design options.
- Minimizes contamination risks in cleanroom settings with robust emission control.
- Meets stringent biopharmaceutical standards, ensuring regulatory compliance.
- Applications
- Biopharmaceuticals,Liquid formulations,Pharmaceutical products
- End products
- Biologic drugs,Intravenous fluids,Protein therapeutics,Vaccine suspensions,Gene therapy vectors,Liquid oral medicines,Monoclonal antibodies,Plasma derivatives,Injectable antibiotics,Insulin solutions,Cell culture broth,Serum albumin
- Steps before
- Purification,Emulsification,Grinding
- Steps after
- Sterilization,Packing
- Input ingredients
- biopharma products,shear sensitive products,cells,low and medium solid contents,solids up to 10 vol%,solid contents from 10 to 35 vol%
- Output ingredients
- clarified biopharma products,high separation performance products,aseptic pharmaceuticals
- Automation
- Automatic SIP/CIP
- Capacity
- Full range,four bowl sizes
- Bowl Design
- High Sigma clarifier or HighVol clarifier
- Solid Content Capacity
- Up to 5 vol% or 10 vol%
- Direct Drive System
- Integrated Direct Drive (IDD) with water-cooled motor
- Shear Force Management
- No shear forces due to hydrohermetic inlet
- Material Handling
- Smooth,no turbulence
- Skid Design
- Optimized skid design
- Working mechanism
- Hydrohermetic inlet,Direct Drive
- Batch vs. continuous operation
- Inline Continuous
- CIP/SIP
- Automatic SIP
- Changeover time
- Fast,due to standardized skids
- Automation level
- Automatic SIP and CIP
- Integrated steps
- Clarification,aseptic processing
- Density/particle size
- 0.5–2.5 g/cm³ / 50–1000 µm
- Discharge method
- Nozzle separator skid
- Machine footprint
- Plug,produce pharma skids
- Bowl design
- High Sigma / HighVol clarifier bowl
- Control System
- PLC / SCADA integration
- Bowl Size Options
- Four different sizes
- Skid Design
- Plug,Produce Skid
- Bowl Design
- High Sigma / HighVol clarifier bowl
- Drive System
- Integrated Direct Drive (IDD)
- Solid Content Handling
- Nozzle separator for 10–35 vol%
- Market info
- GEA is known for its expertise in engineering innovative and sustainable equipment and solutions, focusing on sectors such as food, beverages, pharmaceuticals, and energy, with a reputation for quality, efficiency, and advanced technological applications in industrial processing.