Bioprocess sensor for accurate measurement
Optimize your bioprocessing with advanced sensors designed to deliver precise measurements critical to maintaining cell productivity and product stability.
The Applikon AppliSens Bioprocess Sensor Suite is designed to provide continuous, precise monitoring of key parameters in bioprocess environments, making it invaluable for pharmaceutical manufacturers and research laboratories. Featuring advanced sensors for dissolved oxygen (DO2), pH, and RedOx, this suite offers long-term stability and low sensitivity to fouling, ensuring accurate measurements even in challenging conditions. The optical DO sensors utilize RedFlash technology for low oxygen concentration accuracy and reduced maintenance needs. Ideal for applications in cell cultures, batch processes, and continuous production, AppliSens sensors support critical production of monoclonal antibodies, recombinant proteins, and biosimilars. With a robust design for repeated sterilization cycles and compatibility with cGMP requirements, this suite integrates seamlessly into your bioprocessing facility, allowing for efficient optimization and control. Additionally, the suite’s compact sensor heads and standardized connectors facilitate easy setup and interchange with existing bioreactor systems.
Benefits
- Enhances process accuracy by providing real-time monitoring of critical bioprocess parameters.
- Minimizes maintenance requirements with long-lasting sensor design and reduced need for recalibration.
- Supports diverse cultivation environments, including anaerobic and perfusion cultures, for increased production versatility.
- Meets cGMP standards, ensuring compliance and safety in pharmaceutical manufacturing.
- Integrates seamlessly with existing systems, offering flexibility and ease of use.
- Applications
- Microbial cultures,Anaerobic cultures,Fine chemicals,Cell cultures,Nutraceuticals,Continuous cultures,Research laboratories,Biopharmaceuticals,Fed-batch cultures,Perfusion cultures,Pharmaceutical production,Batch cultures
- End products
- Cell therapy products,Vaccines,Biodegradable plastics,Alcohol derivatives,Insulin,Active pharmaceutical ingredients (apis),Monoclonal antibodies,Fermentation-based vitamins,Biosimilars,Antibiotics,Probiotic supplements,Enzymes,Biopolymer products,Recombinant proteins
- Steps before
- Preparation of bioreactor,Autoclaving,Media preparation,Cell inoculation
- Steps after
- Sterilize-in-place (SIP),Clean-in-place (CIP),Product analysis,Packing
- Input ingredients
- cell cultures,microbial cultures,anaerobic cultures,micro-aerobic cultures,growth medium components
- Output ingredients
- biomass density,metabolite concentrations,fermentation acids,hydrogen,product yield
- Diameter
- 8 mm,12 mm
- Insertion Length
- 70 mm,110 mm,235 mm,325 mm,425 mm,590 mm
- Insertion Length for Mini Bioreactor
- 115 mm,135 mm,150 mm,170 mm,185 mm
- Measurement Range
- 0 - 250% (Air),0 - 50% (Oxygen)
- Measurement Range Temperature
- 0 – 70 °C
- PH Measurement Range
- 0 - 12
- Drift
- ,lt
- 2% per week
- Glass Tube Life Time
- Minimum 20 autoclave cycles
- Signal Type
- Digital (Optical Sensor),Analog nA (DO2 Sensors),Analog mV (pH and RedOx Sensors)
- Sensor Connection
- Magnetic (Optical),K9 (DO2,pH,RedOx)
- Communication Type
- Analog mV
- Measurement Principle
- Optical
- Automation level
- Manual / PLC / SCADA
- Batch vs. continuous operation
- Batch / Inline Continuous
- CIP/SIP
- CIP 121°C / SIP 135°C
- Energy efficiency
- 0.5–2 kWh/kg moisture
- Cleaning method
- CIP / Manual
- Density/particle size
- 0.5–2.5 g/cm³ / 50–1000 µm
- Diameter
- 8-12 mm
- Insertion length
- 70-590 mm
- Glass tube life time
- Minimum 20 autoclave cycles
- Sensor connection
- Magnetic,K9
- Control panel type
- Standardized PG 13.5 connection
- Interchangeability
- Compatible with other bioreactor brands
- Sensor design
- Compact design,robust tempered glass shaft
- Market info
- Getinge is known for providing innovative healthcare and life sciences products, specializing in medical technology, infection control, surgical workflows, and critical care solutions. They maintain a strong reputation for quality and technological advancement in these sectors.