Clarifiers for blood processing
Ensure optimal separation of blood components with precision engineering for aseptic processing, enabling the production of high-purity plasma protein concentrates and sterile injectable drugs while maintaining stringent temperature controls.
The Clarifier Hycon from GEA is a centrifugal separator engineered for sterility in blood and biopharmaceutical processing. It unifies chamber and self-cleaning separator advantages to maximize separation efficiency while maintaining a hermetic environment. The system utilizes a steam-sterilized, fully enclosed design, ideal for producing plasma protein concentrates, monoclonal antibodies, and aseptic fill-finish products. Achieving controlled product temperatures of -3 to -6°C through direct nitrogen cooling, it supports processes where precise thermal management is essential. The unit meets GMP standards, ensuring compliance in pharmaceutical environments, and its hermetic isolation aids in economical cleanroom integration. Automated, continuous operation and integrated safeguards facilitate reduced manual oversight, while customizable configurations offer flexibility for unique process requirements.
Benefits
- Ensures product integrity with aseptic processing conditions.
- Maintains precise temperature control, crucial for sensitive biopharmaceuticals.
- Enhances operational efficiency through continuous, automated operation.
- Minimizes contamination risk with hermetically sealed design.
- Complies with stringent GMP standards, facilitating regulatory approval.
- Applications
- Aseptic processes,Biopharmaceuticals,Blood processing,Pharmaceutical processes
- End products
- Blood plasma derivatives,Sterile injectable drugs,Plasma protein concentrates,Monoclonal antibodies,Antibiotics,Biopharmaceutical vaccines,Immunoglobulins,Aseptic fill-finish products,Bulk pharmaceutical chemicals
- Steps before
- Blood collection,Pre-cooling,Initial filtration
- Steps after
- Sterilization,Product packaging,Quality inspection
- Input ingredients
- { "input": ["blood", "biopharma products", "low solid content materials"], "output": ["high concentration solids", "separated liquid"]; }
- Output ingredients
- { "input": ["blood", "biopharma products", "low solid content materials"], "output": ["high concentration solids", "separated liquid"]; }
- Market info
- GEA is known for its expertise in engineering innovative and sustainable equipment and solutions, focusing on sectors such as food, beverages, pharmaceuticals, and energy, with a reputation for quality, efficiency, and advanced technological applications in industrial processing.
- Aseptic process
- Yes
- Solids concentration
- High
- Hermetic isolation
- Yes
- Temperature range
- -3 to -6 °C
- Cooling system
- Direct nitrogen cooling
- Temperature tolerance
- ±1°C
- Sanitary standards
- High surface quality
- Sterile process system
- Steam-sterilized (SIP)
- Product handling
- Hermetic inlet,gentle draining
- Batch vs. continuous operation
- Batch / Inline Continuous
- Automation level
- Manual / PLC / SCADA
- CIP/SIP
- CIP 121°C / SIP 135°C
- Cleaning method
- CIP / Manual
- Energy efficiency
- 0.5–2 kWh/kg moisture
- Density/particle size
- 0.5–2.5 g/cm³ / 50–1000 µm
- Sterility Assurance Level
- SIP (Steam-In-Place) Capable
- Machine footprint
- Compact
- Bowl Type
- Hermetic
- Discharge Method
- Self-cleaning
- Shape
- Vessel concept
- Control panel type
- HMI/Touchscreen
- Integration possibilities
- PLC/SCADA systems
- Temperature control method
- Nitrogen cooling
- Operation environment
- Clean room conditions
- Sterilization method
- Steam-sterilized system (SIP)
- Solids handling
- Suspended vessel concept
- Material handling
- Hermetic inlet and gentle draining
- Automation level
- Automatic/Manual
- Temperature range
- -3 to -6 °C