Clean-in-place systems for biotechnology and pharma

Ensure seamless transitions between production batches with efficient, high-performance cleaning systems tailored to maintain peak hygiene and operational precision in complex liquid formulation processes.

The Clean-In-Place Systems from BRS Biotech are designed to meet the stringent demands of the biotech, pharmaceutical, and food processing industries by ensuring meticulous cleaning of fermentors, vessels, and piping systems. These systems utilize a single-pass or multi-circuit operation with automatic control to manage temperature, time, and cycle, which facilitates efficient cleaning and preparation between production batches. Suitable for applications ranging from monoclonal antibodies and insulin production to sauces and plant-based milk formulations, these systems accommodate vessel volumes between 150 to 600 liters.

Constructed from SUS316L stainless steel, they offer superior corrosion resistance, essential for maintaining integrity in aggressive environments. Operating at a maximum temperature of 85°C and with a solution flow rate ranging from 10-25 m³/h, they meet various cleaning needs. Energy efficiency is enhanced through precise control systems, and the optional provision of GMP documentation ensures adherence to industry standards. Designed for seamless integration into existing production lines, they support both batch and automatic operations, offering flexibility and reliability for diverse production demands.

Benefits

  • Enhances production efficiency by ensuring rapid and thorough equipment cleaning.
  • Lowers operational costs with automatic control systems, minimizing manual intervention.
  • Preserves product integrity through precise cleaning tailored to biopharmaceutical and food standards.
  • Supports compliance with industry regulations with available GMP documentation.
  • Increases equipment lifespan with corrosion-resistant SUS316L construction.
Applications
Sauces,Liquid formulations,Fine chemicals,Fermented products,Nutraceuticals,Biopharmaceuticals,Enzymes,Biofuel,Baby food,Plant-based milk,Pharmaceuticals
End products
Paracetamol,Ketchup,Ethanol,Lipase enzymes,Insulin,Infant formula,Monoclonal antibodies,Cough syrup,Almond milk,Omega-3 supplements,Yogurt
Steps before
Setup,Installation,Loading
Steps after
Sterilization,Product Changeover,Equipment Inspection
Input ingredients
Output ingredients
Vessel volume
150-600 L
Vessel material
SUS316L
Voltage
3×400 VAC,60 Hz
Solution flow
10-25 m³/h
Max temperature
85 °C
Circuits
Single-pass or multi-circuit
Control
Automatic control
Cleaning method
CIP / Automatic
Automation level
Automatic control
Batch vs. continuous operation
Single-pass or multi-circuit
Control system
Automatic solution return
Temperature control
Max temperature 85°C
Energy source
Voltage 3×400 VAC,60 Hz
Corrosive resistance (e.g. acids)
SUS316L
Tank volume
150-600 L
Tank material
SUS316L
Max temperature
85 °C
Solution flow rate
10-25 m³/h
Voltage
3×400 VAC,60 Hz
Control type
Automatic control
Installation
Swift and simple
Installation type
Swift and simple installation
Maintenance requirement
Easy maintenance and operation
Market info