Cryogenic ball grinder for laboratory use
Achieve precise temperature-controlled grinding with advanced cryogenic technology, ensuring preservation of volatile components while transforming tough, thermally sensitive materials seamlessly into fine powders for consistent, high-quality results every time.

The CryoMill from Retsch is a cutting-edge laboratory ball mill designed specifically for cryogenic grinding, ensuring high efficiency and operational safety throughout the process. This system incorporates an integrated autofill liquid nitrogen cooling feature that maintains a consistent temperature of -196°C, allowing the material to remain embrittled during milling. Its powerful grinding mechanism by impact and friction processes materials such as pharmaceuticals, polymers, chemicals, and biological samples into fine powders, ideal for detailed analyses.
With a maximum feed size of 8 mm and a final fineness of approximately 5 µm, the CryoMill efficiently homogenizes, mixes, and disrupts cells, offering versatility for applications in various industries, including biotechnology, environmental sciences, and food processing. This bench-top model accommodates one grinding station compatible with jars ranging from 5 to 50 ml, with adapters available for even smaller quantities.
Energy-efficient and user-friendly, the CryoMill provides customizable digital settings with programmable parameters, ensuring precise control over the grinding cycles. Its closed LN2 system enhances user safety by preventing direct contact with liquid nitrogen, and the equipment is built to reduce operational disruption. Constructed with durable materials such as stainless steel and zirconium oxide, the CryoMill can be tailored to resist corrosion and contamination based on your specific needs. This laboratory mill meets CE compliance standards, making it a reliable choice for research institutions and industrial settings by R&D professionals.
Benefits
- Ensures consistent particle size and integrity with precise cryogenic milling.
- Enhances user safety by eliminating direct contact with liquid nitrogen.
- Increases productivity with programmable, automated grinding cycles.
- Versatile grinding capabilities for a wide range of sample types and sizes.
- Minimizes sample degradation with rapid processing and integrated cooling.
- Applications
- Chemicals,Food,Animal feed,Ceramics,Metallurgy,Medicine,Geology,Biology,Plants,Waste,Plastics,Oil seed,Soil,Textiles,Recycling,Pharmaceuticals
- End products
- Food powders,Textile fibers,Compost additives,Botanical extracts,Synthetic polymers,Plant-based oils,Dna/rna samples,Chemical additives,Plastic granules,Recycled material aggregates,Medical powders,Ceramic powders,Mineral samples,Pharmaceutical powders,Livestock feed supplements,Metallurgical samples
- Steps before
- Sample Preparation,Cooling,Pre-cooling
- Steps after
- Homogenization,Mixing,Size Reduction
- Input ingredients
- waste,soil,chemical products,tissue,hair,wood,sewage sludge,bones,plastics,oil seed,paper,plants,pills,textiles,animal feed,wool,rubber duck,hard plastic,gummy bears
- Output ingredients
- pulverized materials,size reduction,homogenized samples,mixed samples,cell disruption
- Grinding speed
- Max. 30 Hz
- Feed size
- Up to 8 mm
- Final fineness
- Approx. 5 µm
- Batch size
- Max. 20 ml
- Grinding jar sizes
- 5 ml,10 ml,25 ml,35 ml,50 ml
- Grinding modes
- Cryogenic,dry,and wet
- Vibrational frequency
- 5 - 30 Hz
- Material of grinding tools
- Hardened steel,stainless steel,zirconium oxide,PTFE
- Power consumption
- 260 W
- Electrical supply
- 100-240 V,50/60 Hz
- Protection code
- IP 30
- Cooling temperature
- -196°C
- Cooling method
- Liquid nitrogen,autofill system
- Autofill capacity
- 50 liters
- Oscillation principle
- Horizontal radial oscillations
- Dimensions (W x H x D)
- 395 x 373 x 577 mm
- Net weight
- Approx. 45 kg
- Storable SOPs
- 9 programmable cycles
- Grinding time
- 10 min average
- Working mechanism
- Impact ball milling
- Integrated steps
- Cooling with liquid nitrogen
- Batch vs. continuous operation
- Batch
- Automation level
- Digital control with programmable cycles
- Cleaning method
- Safe handling features
- Energy efficiency
- 260 W power consumption
- Safety features
- Closed LN2 system
- Density/particle size
- 0.5–2.5 g/cm³ / 50–1000 µm
- Compact footprint
- Bench top model
- Control panel type
- Digital keypad with structured interface
- Discharge method
- Single grinding station with oscillation
- Grinding jar sizes
- 5 ml,10 ml,25 ml,35 ml,50 ml
- Cooling system
- Integrated with liquid nitrogen autofill
- Grinding modes
- Cryogenic,dry,wet
- Control panel type
- Digital keypad
- Integration possibilities
- Connection to cryo tanks with safety valve
- Grinding jar material options
- Hardened steel,stainless steel,zirconium oxide,PTFE
- Cooling system
- Integrated autofill system with liquid nitrogen
- Jar size customization
- 5 ml / 10 ml / 25 ml / 35 ml / 50 ml
- Programmable cycles
- 9 programmable cooling and grinding cycles
- Market info
- RETSCH is known for its high-quality laboratory equipment for sample preparation and particle size analysis, including mills, crushers, and sieve shakers, praised for their precision, durability, and reliability in research and industrial applications.