High-capacity centrifuge for vaccine purification
Optimize vaccine production with high-speed centrifuging that ensures precise and efficient purification of viral vectors and proteins, critical for maintaining high-quality standards.
The Sorvall CC40NX and CC40SNX centrifuges from Thermo Scientific are engineered for biopharmaceutical manufacturers and vaccine producers requiring precise purification and separation of biomaterials. These centrifuges feature an induction drive for continuous or batch processing, operating up to 40,000 rpm with an FCR of 118,000 x g to handle demanding applications such as recombinant insulin and viral vector production.
Ideal for both high-volume and small-scale operations, the CC40NX manages up to 8.0L in batch mode and 3.2L in continuous flow. Automation includes a micro-processor controlled digital display, ensuring simplified monitoring and control, while an oil rotary vacuum pump maintains optimal conditions during operation.
The robust design includes corrosion-resistant stainless steel, adhering to US FDA cGMP and CE standards, ensuring compliance with pharmaceutical regulations. Maintenance is streamlined with automated diagnostics and a backup system for motor lubrication continuity. Configurations can be customized with various rotors and accessories to meet specific operational needs, making integration within existing production lines seamless and efficient.
Benefits
- Enhances product yield with high-speed purification and separation processes.
- Reduces operational interruptions through automated error detection and diagnostics.
- Meets stringent pharmaceutical standards, ensuring regulatory compliance.
- Simplifies system integration with a compact design and flexible rotor configurations.
- Optimizes processing efficiency with variable speed control, minimizing energy costs.
- Applications
- Proteins,Vaccines,Viral vectors,Biopharmaceuticals,Pharmaceutical ingredients
- End products
- Monoclonal antibodies,Adeno-associated viral vector,Recombinant insulin,Hepatitis b vaccine,Protein therapeutics
- Steps before
- Sample preparation,Preclarification,Mixing
- Steps after
- Purification,Separation,Analysis,Filtration
- Input ingredients
- virus,proteins,HBsAg,large sample volumes,vaccines,liposomes
- Output ingredients
- purified virus,purified proteins,gradient density preparations,centrifuged HBsAg,purified vaccines
- Capacity
- 1.6L
- Capacity
- 8.0L (lot),3.2L (continuous)
- Electrical Supply
- 200/208/220/230/240 V ±10% 50/60 Hz
- Drive System
- Induction
- Temperature Range
- 0 ° to 40 ° C,± 2 °
- Max RCF
- 118000 x g
- Max Speed
- 40000 rpm
- Adjustable Speeds
- Up to 40,000 rpm,± 100 rpm
- Display
- Digital
- Max Vacuum
- 26.7 per year (0.2 torr)
- Vacuum System
- Oil rotary vacuum pump
- Noise Level
- 68 dBA at 40,000 rpm
- Automation
- Micro-computer controlled,Automated operation
- Self-diagnostic
- Generates alarms and error codes
- Automation level
- Automated with microcomputer control
- Batch vs. continuous operation
- Batch / Continuous
- Cleaning method
- CIP / Manual
- Changeover time
- Minimal due to automated system
- Energy efficiency
- High efficiency due to advanced motor design
- Temperature control
- 0 ° to 40 °C,± 2 °C
- Vacuum system
- Oil rotary vacuum pump
- Noise level
- - 68 dBA at 40,000 rpm
- Flexibility of configuration
- Variety of rotors and accessories
- Control panel
- Digital display with user interface
- Operation in case of power failure
- Automatic lubrication and maintenance
- Error detection
- Automatic error diagnosis and reporting
- Reliable performance
- Automated with error detection
- Corrosion Resistance
- Yes
- Biological Compatibility
- Complies with CGMP
- Cleanability
- Stainless Steel Components
- Compact footprint
- Reduced footprint for space efficiency
- Control panel type
- Digital control panel
- Discharge method
- Continuous flow/discharge
- Machine capacity
- 8.0L (batch),3.2L (continuous)
- Compact footprint
- Designed for high volume processing
- Machine design
- Corrosion-resistant stainless-steel components
- Temperature range
- 0° to 40°C,±2°C
- Vacuum system
- Oil rotary vacuum pump
- Compact footprint
- Reduced physical space requirement
- Control panel type
- Digital control panel
- Discharge method
- Various rotor and accessory configurations
- Market info
- Thermo Fisher Scientific is renowned for providing innovative scientific instruments, laboratory equipment, and engineered-to-order solutions across various industries, esteemed for their high-quality products and expertise in life sciences, pharmaceuticals, and biotechnology sectors.