Lab equipment for web processing in Tts/tds and Odf production
Streamline the development and production of sensitive therapeutic films and patches with a compact lab solution that seamlessly adapts from research to pilot-scale manufacturing, ensuring precise handling and integration into existing processes.
The PML lab machine from Harro Höfliger offers a versatile solution for processing transdermal therapeutic systems and oral dissolvable films, specifically tailored for R&D and small-scale production needs. This equipment processes sensitive materials using precise web handling, punching, sealing, and packaging, ensuring accurate quality control and flexible batch operations. It is designed for pharmaceutical and medical device manufacturers focused on developing nicotine, fentanyl, and hormone therapy patches, as well as vitamin B12 and sleep aid films. With a processing capacity of up to 40 products per minute and a maximum web width of 100 mm, the PML provides seamless integration of upstream and downstream processes, offering a customizable, modular setup for various batch sizes. Its open design allows for future process modifications, making it adaptable for evolving production requirements. Additionally, it employs advanced inspection systems to maintain rigorous quality standards, adhering to GMP and FDA guidelines, and ensuring compliance for sensitive pharmaceutical applications.
Benefits
- Enhances R&D efficiency by easily transitioning from lab-scale to high-volume production.
- Maintains product integrity with gentle handling of sensitive materials like oral films.
- Customizable modules allow for tailored configurations to meet specific production needs.
- Ensures high-quality output with advanced camera inspection systems.
- Complies with pharmaceutical standards, facilitating regulatory approval processes.
- Applications
- Oral dissolvable films,Transdermal therapeutic systems,Matrix patches,Reservoir patches
- End products
- Caffeine patches,Fentanyl patches,Anti-allergy oral dissolvable films,Nicotine patches,Sleep aid oral dissolvable films,Lidocaine patches,Hormone replacement therapy patches,Vitamin b12 oral dissolvable films
- Steps before
- Research and Development,Material Selection,Substrate Preparation,Web Handling Setup
- Steps after
- Packing,Quality Inspection,Contour Cutting,Sealing
- Input ingredients
- transdermal TTS/TDS therapeutic systems,Oral Dissolvable Films (ODF),web material up to 100 mm width,substrate for TTS/TDS patches,thin,sensitive oral film strips
- Output ingredients
- ODF – Oral Dissolvable Film,TDS – Matrix patch standard/special design,TDS – Reservoir patch,TTS – Transdermal therapeutic systems
- Output
- 40 products/min
- Web width
- max. 100 mm
- Final products
- ODF – Oral Dissolvable Film
- Final products
- TDS – Matrix patch standard/special design
- Final products
- TDS – Reservoir patch
- Final products
- TTS – Transdermal therapeutic systems
- Processing substrate
- TTS/TDS patches
- Automation
- Flexible and adjustable
- Batch series
- Lab and batch machines
- Flexible design
- Yes
- Operator friendly
- Yes
- Batch vs. continuous operation
- Batch
- Production scalability
- Lab to high performance
- Web width
- Max. 100 mm
- Production rate
- 40 products/min
- Web processing type
- Intermittent
- Contour cutting
- Yes
- Process modification capability
- Yes
- Material handling
- Gentle
- Precision punching
- Yes
- Sealing technologies
- Platen,roller,pulse,ultrasonic,thermal
- Density/particle size
- 0.5–2.5 g/cm³ / 50–1000 µm
- Compact footprint
- Yes
- Web width
- Max. 100 mm
- Discharge method
- Contour cutting and punching
- Control panel type
- Flexible and adjustable
- Control panel type
- Operator-friendly,adjustable
- Integration possibilities
- Flexible expansion with modules
- Design configuration
- Compact,clear,open design
- Modular options
- Flexibly configurable for batch series
- Footprint
- Compact
- Process modification
- Processes and options can be supplemented/modified
- Market info
- Harro Hoefliger is known for its expertise in manufacturing custom, engineered-to-order packaging and production equipment, particularly for the pharmaceutical, healthcare, consumer goods, and chemical industries, with a reputation for precision, innovation, and quality engineering solutions.