Pharmaceutical centrifuge for particle separation

Effortlessly upscale your biopharmaceutical processes with a compact centrifuge that handles demanding separation tasks, ensuring precise particle separation and product consistency across varying batch sizes.

The GEA pathfinder GMP, from the renowned GEA Group, is a pharmaceutical separator skid engineered for biopharmaceutical applications including cell harvesting and clarification of monoclonal antibodies, vaccines, and recombinant proteins. Its compact design fits seamlessly into your existing production lines, offering plug-and-play convenience with fully integrated connections and controls. Utilizing a hydrohermetic feed system, it ensures gentle treatment of shear-sensitive microorganisms, while the GEA hydrostop system allows for controlled partial ejections. With a processing capacity ranging from 15 l/h to 300 l/h, it maintains high throughput in both batch and pilot operations. Fabricated from high-alloy stainless steel 316L, it offers excellent corrosion resistance and complies with GMP and FDA standards, ensuring product safety and quality. The system comes with full documentation, including material and surface quality certificates, and supports easy bowl exchange to adapt to varying batch sizes. Additionally, its CIP capability and low-maintenance design streamline cleaning and reduce downtime, making it a versatile and efficient solution for pharmaceutical manufacturers, CMOs, and biotech companies.

Benefits

  • Enhances product quality with precise separation of challenging biopharmaceutical materials.
  • Streamlines setup with plug-and-play integration, reducing installation time.
  • Minimizes maintenance efforts through CIP capability and low-maintenance components.
  • Ensures regulatory compliance with GMP and FDA standards.
  • Facilitates quick adaptation to varying production demands with easy bowl exchange.

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Applications
Biopharmaceuticals,Pharmaceutical applications,Cell harvesting
End products
Recombinant proteins,Vaccines,Insulin,Monoclonal antibodies,Cell culture media
Steps before
Formulation Preparation,Dissolution,Feeding
Steps after
CIP (Clean-in-Place) Operations,Sanitization,Quality Inspection,Documentation,Storage
Input ingredients
pharmaceutical slurry,liquid with shear-sensitive microorganisms,fine particles with slight density differences
Output ingredients
clarified liquid,separated particles,concentrated microorganisms
Automation
Plug,play
Capacity
15 l/h – 300 l/h
Separation force
20,000 g
Bowl sizes
Three bowl sizes
Material quality
316L stainless steel
Surface quality
0.8 μm
Temperature tolerance
up to 100 °C
Pressure tolerance for cooling system
up to 1.5 bar overpressure
Bowl exchange adaptability
3 in 1
Noise level
Low running noise
Belt drive type
Low-maintenance flat belt
Pre-installation
On a frame including piping and control cabinet
Vibration monitoring
Available option
Turbidity meter
Available option
Pumps available
Feed and solids pump
Control system
Siemens or Alan-Bradley
CIP capability
Included (spray nozzles)
Batch vs. continuous operation
Batch / Inline Continuous
Automation level
Manual / PLC / SCADA
Cleaning method
CIP / Manual
Energy efficiency
Not specified
Plug,play installation
Yes
Changeover time
Not specified
Hydrohermetic feed system
Yes
Controlled partial ejections
Through GEA hydrostop system
Sound level
Low running noise
All-in-one unit installation
Yes
Cleanability
Optimal Cleanability
Density
0.5–2.5 g/cm³
Particle size
50–1000 µm
Machine footprint
Compact
Skid format
Sophisticated compact
Door size requirement
900 mm
Bowl sizes
Three sizes available
Flow rate
15 l/h – 300 l/h
Control panel type
Alan-Bradley / Siemens
Discharge method
GEA hydrostop system
Compact footprint
Fits through a 900-mm door
Integration possibilities
Pre-installed connections and control modules
Market info
GEA is known for its expertise in engineering innovative and sustainable equipment and solutions, focusing on sectors such as food, beverages, pharmaceuticals, and energy, with a reputation for quality, efficiency, and advanced technological applications in industrial processing.