Pilot industrial tangential flow filtration system

Enhance precision in filtration and separation processes with this system designed to streamline complex purification cycles in the biopharmaceutical and chemical sectors, ensuring optimal retention and concentration of valuable components throughout production.

The TFF TYTAN from Solaris Filtration Systems is a versatile tangential flow filtration system designed to tackle complex processing challenges in biopharmaceuticals, fine chemicals, and nutraceuticals. It utilizes a robust cross-flow technique with ceramic and polymeric membranes available in pore sizes from 0.04µm to 1.2µm, ideal for separating and concentrating various liquid formulations. Specifically, it excels in the production of monoclonal antibodies, vaccine components, and enzyme solutions. Offering scalable throughput with up to 120 modules, the system is PLC-controlled, supporting automatic operation and remote monitoring via the LEONARDO SCADA software. Constructed with corrosion-resistant AISI 316 and AISI 304 stainless steel, it ensures durability and compliance with GMP and PED standards. The system’s inline Clean-in-Place (CIP) capability allows for efficient maintenance, minimizing downtime. Custom configurations integrate membrane types such as spiral wound, hollow fiber, and tubular designs to meet specific operational demands, with technical support available to refine and optimize your process.

Benefits

  • Enhances efficiency by reducing processing time with automated filtration and CIP programs.
  • Offers flexibility with customizable membrane configurations to meet diverse product specifications.
  • Ensures product integrity with seamless integration into existing production lines.
  • Minimizes maintenance efforts with robust stainless steel construction and integrated SCADA monitoring.
  • Supports regulatory compliance with GMP and PED standards for pharmaceutical applications.
Applications
Liquid formulations,Fine chemicals,Nutraceuticals,Biotechnological products,Biopharmaceuticals
End products
Protein powders,Batch cultures for probiotics,Herbal extract supplements,Monoclonal antibodies,Enzyme solutions,Lyophilized drug formulations,Liquid protein formulations,Vaccine components
Steps before
Purification,Emulsification
Steps after
Concentration,Separation,Buffering,Sterilization
Input ingredients
unfiltered product,retentate
Output ingredients
permeate,concentrated biotechnological products
Membrane Pore Size
0.04µm to 1.2µm
Number of Modules
Up to 120
Material
Stainless steel (AISI 316 and AISI 304)
HMI Touch Panel Size
21.5”
Backwash
Automatic
Filtration and CIP-Programs
Automatic
SCADA Software
LEONARDO 3.0
Remote Access
PC,tablet,smartphone
Filtration Configuration
Spiral wound,hollow fiber,cassettes,tubular
Control System
SCADA supervisory Lab View,SFC-10,PLC
Centrifugal Pumps
For supply and transfer
Tanks
Available for filtrate and retentate
Working mechanism
Tangential flow filtration / Cross flow filtration
Integrated steps
Automatic backwash,Filtration and CIP-Programs
CIP/SIP
CIP inline
Batch vs. continuous operation
Batch and inline continuous
Automation level
SCADA / PLC-controlled
Dry running protection
Over- and under-pressure protection
SCADA Software
LEONARDO 3.0
Remote access
PC,tablet or smartphone
Corrosive resistance
Stainless steel (AISI 316 and AISI 304)
Material of Construction
Stainless steel (AISI 316 and AISI 304)
Membrane Pore Size Range
0.04µm to 1.2µm
Tank Options
Available to buffer filtrate and retentate
Control Panel Type
21.5” HMI touch panel
Number of Modules
Up to 12
Control panel type
21,5” HMI touch panel
Material choice
Stainless steel (AISI 316 and AISI 304)
Membrane types
Ceramic and polymeric
Membrane configuration
Spiral wound / Hollow fiber / Cassettes / Tubular
Pore sizes
0.04µm to 1.2µm
Automation level
SCADA with LEONARDO 3.0 software
System Integration
Smart sensor technology
Tank options
Available for buffering filtrate and retentate
Market info
Solaris Biotech is known for manufacturing specialized engineered-to-order bioprocessing equipment, including fermenters and bioreactors, with a strong reputation for innovation, quality, and customization capabilities in the biotechnology and pharmaceutical markets.