Production-level ultrafiltration system for industrial applications
Achieve precise concentration and separation of valuable biomolecules while maintaining product integrity and compliance with stringent regulatory standards across continuous and automated production processes.
The AutoTFF series from TRUKING TECHNOLOGY LIMITED is designed for precise ultrafiltration and concentration of pharmaceutical products. This system uniquely incorporates flow feedback control and automated TMP management, ensuring consistent processing across a range of applications such as vaccine production, monoclonal antibodies, and liquid-filled ampoules. With the capability to handle both pilot and full-scale production, it integrates smoothly into existing lines with PLC control and real-time data recording. Energy efficiency is enhanced with an optimized rotor pump system. The equipment is constructed from corrosion-resistant materials, ensuring long-lasting performance and compliance with FDA and GMP standards for pharmaceutical applications. Maintenance is streamlined with an integrated CIP system, allowing quick and efficient cleaning between batches. Customization options allow adaptation to specific production needs, supported by TRUKING’s engineering and technical expertise.
Benefits
- Enhances product purity and yield with precise control of ultrafiltration parameters.
- Minimizes operational costs through automated monitoring and adjustments.
- Increases process efficiency, integrating seamlessly into continuous production lines.
- Complies with GMP and FDA standards, ensuring regulatory compliance.
- Simplifies maintenance with an integrated CIP system for fast, efficient cleaning.
- Applications
- Injectable,Softbag production,Lyophilization production,Diagnostic reagents,Bfs production,Pre-filled syringe production,Ampoule production,Oral preparation
- End products
- Vaccines,Iv fluid bags,Pre-filled insulin syringes,Monoclonal antibodies,Tablets,Diagnostic test kits,Oral liquid vitamins,Freeze-dried pharmaceuticals,Lyophilized anti-cancer drugs,Bfs eye drops,Bfs saline solutions,Capsules,Liquid-filled ampoules
- Steps before
- Extraction,Concentration,Purification,Reaction
- Steps after
- Sterilization,Packing,Inspection,Labeling
- Input ingredients
- raw pharmaceutical ingredients,biological materials,liquid formulations,solid formulations,chemical substances,traditional Chinese medicine extracts,diagnostic reagents
- Output ingredients
- freeze-dried products,injectables,lyophilized vials,ampoules,pre-filled syringes,soft bags,oral liquid medications,finished pharmaceutical goods
- Automation
- Independently developed control software,comply with FDA regulations
- Control Method
- Flow feedback control,automatically real-time adjustment of rotor pump speed
- Data Management
- Stable and reliable data management,real-time recording,no data loss after power failure
- Interface
- Menu-based,simple and straightforward
- Membrane Fixture
- Equip standard ultrafiltration membrane fixture with brand ultrafiltration membrane package
- Proportional Valve Adjustment
- Precise opening adjustment for precise control of TMP
- Sensors
- Customized flow and temperature sensor devices
- Database Management
- Real-time recording,no data loss during blackout
- Diaphragm Pump
- Use imported biological special diaphragm pump to reduce protein fragmentation rate
- Control of TMP
- Automatic
- Membrane Compatibility
- Compatible with various mainstream membrane packages
- Weighing System
- Automatic and accurate control of concentration volume and feeding speed
- Liquid Storage Tank
- With respirator and anti-vortex function,optional flow and rehydration module
- Cleaning
- Self-draining and clean in place (CIP)
- Automation level
- Manual / PLC / SCADA
- CIP/SIP
- CIP 121°C / SIP 135°C
- Cleaning method
- CIP / Manual
- Energy efficiency
- 0.5–2 kWh/kg moisture
- Batch vs. continuous operation
- Batch / Inline Continuous
- Density/particle size
- 0.5–2.5 g/cm³ / 50–1000 µm
- Flow sensor type
- Customized
- Temperature sensor type
- Customized
- Control software
- Independently developed,FDA compliant
- Software interface
- Simple,menu-based
- Membrane fixture compatibility
- Brand ultrafiltration membrane packages
- Automation level
- Real-time automatic adjustment
- Market info
- Truking is known for manufacturing engineered-to-order pharmaceutical equipment, specializing in liquid and solid preparation systems. They have a strong reputation for innovation and quality in the pharmaceutical machinery sector.