Real-time Uv-vis analysis for dissolution testing
Efficiently perform dual dissolution tests simultaneously, seamlessly integrating UV-Vis spectrophotometry to meet stringent pharmacopeia standards without media replacement, enhancing real-time analysis and overall workflow.
The ATS Xtend™ Double UV Online from SOTAX is a cutting-edge dissolution testing system designed for pharmaceutical applications. It enables real-time analysis of up to 16 samples using a high-performance double beam UV-Vis spectrophotometer. The system facilitates simultaneous testing and analysis, connecting two dissolution testers to a single spectrophotometer, which optimizes lab space and reduces investment costs. Ideal for applications involving aspirin tablets, protein powders, and injectable suspensions, among others, it’s versatile in supporting a wide range of pharmaceuticals and medical devices. The system seamlessly integrates into existing workflows with automated sampling, filtration, and return processes, eliminating media replacement needs. It ensures full compliance with Pharmacopeia and 21 CFR part 11 regulations and supports easy expansion with modular components, making it scalable and future-proof. Built with stainless steel for durability, the system simplifies maintenance and is customizable to adapt to specific laboratory needs.
Benefits
- Increases efficiency by analyzing up to 16 samples simultaneously.
- Reduces laboratory costs through dual operation with one UV-Vis spectrophotometer.
- Ensures compliance with industry standards including 21 CFR part 11.
- Saves space with compact, integrated design.
- Simplifies scaling operations with modular, expandable components.
- Applications
- Medical devices,Gels,Pellets,Granules,Microspheres,Catalysts,Stents,Nano suspensions,Fine chemicals,Coated lenses,Soft-gelatin capsules,Implants,Capsules,Powders,Washtabs,Transdermal patches,Creams,Suppositories,Semi-solids,Apis,Tablets,Injectable suspensions
- End products
- Anti-reflective coated lenses,Silver nanoparticle suspensions,Fertilizer pellets,Protein powder,Insulin injectable suspensions,Hydrocortisone creams,Ibuprofen active pharmaceutical ingredient,Vitamin d soft-gelatin capsules,Glycerin suppositories,Dishwasher detergent washtabs,Dental implants,Aloe vera gel,Nicotine transdermal patches,Acetic acid,Platinum-based catalysts,Fluorescent microspheres,Cardiac stents,Fish oil capsules,Aspirin tablets,Instant coffee granules
- Steps before
- Media Preparation,Degassing,Heated Medium Dispensing
- Steps after
- Data Management,Result Analysis,Report Generation
- Input ingredients
- dissolution samples,tablets,capsules,pellets,APIs,powders,granules,soft-gelatin capsules,suppositories,medical devices,stents,implants,microspheres,nano suspensions,injectable suspensions,semi-solids,gels,creams,transdermal patches,washtabs,fine chemicals,catalysts,food,animal health,coated lenses
- Output ingredients
- real-time UV-Vis analysis,dissolution results,simultaneous analysis of multiple samples,pharmacopeia-compliant data,21 CFR part 11 compliant data
- Capacity
- Up to 16 samples in real-time
- Automation
- Automated sample preparation and analysis
- Accuracy
- Exceed Pharmacopeia requirements with true double beam UV-Vis technology
- Compliance
- 21 CFR part 11 regulations
- Media Replacement
- No media replacement required for DR and MR methods
- Sampling Flexibility
- Motorized lift-in/out cannulas,through-shaft sampling,or resident probes
- Modules
- Modular,scalable,and future-proof design
- UV-Vis Analysis
- Simultaneous single or multi-wavelength analysis
- Data Management
- q-doc® software with 21 CFR part 11 compliance
- Degassing Capacity
- 10-20 liters of degassed and heated medium
- Automation level
- Automated sampling and analysis
- Real-time analysis
- Yes
- System scalability
- Modular and scalable
- Batch vs. continuous operation
- Continuous
- Sampling method
- Automated with cannula and filter options
- Integration capability
- Seamless UV-Vis integration
- Sample capacity
- Up to 16 samples simultaneously
- Flexible sampling capabilities
- Motorized or through-shaft sampling
- Medium return
- Automatic without media replacement
- Instrument control
- Automated
- Density/particle size
- 0.5–2.5 g/cm³ / 50–1000 µm
- Pharmacopeia Compliance
- USP / EP
- Discharge method
- Automated sampling
- Market info
- Sotax AG is renowned for its expertise in manufacturing high-quality pharmaceutical testing equipment, including dissolution testing systems, and has a strong reputation for reliability, precision, and innovation in laboratory and industrial applications.