Self-cleaning dissolution tester for automated series testing
Achieve unparalleled precision in dissolution testing with an automated system that minimizes hands-on intervention, ensuring consistent and reproducible results across multiple test runs while maintaining stringent compliance with pharmacopeia standards.
The ATF Xtend™ Offline Dissolution Tester from SOTAX revolutionizes your laboratory workflow by implementing a fully automated, self-cleaning system that meticulously manages dissolution testing. This equipment excels in integrating dissolution testing, media preparation, and sample collection, optimizing processes across R&D and quality control environments. Suitable for applications ranging from pharmaceutical tablets to medical device coatings, it ensures precise and reliable results.
Equipped with an integrated media preparation module, the system prepares, heats, and degasses media using various recipes. The high-precision piston pump and automated filtration system support efficient HPLC/UPLC analysis by accommodating filters down to 0.2 microns. The system’s compliance with USP, Ph.Eur., and other pharmacopeias assures 100% traceability and repeatability, making it ideal for maintaining standards in pharmaceutical manufacturing and biotechnology.
Designed for efficiency, the self-cleaning dissolution tester reduces the need for manual intervention, enabling continuous operation with no operator-required vessel removal for cleaning. Additionally, the q-doc® data management software ensures data integrity while adhering to 21 CFR part 11 compliance. With customization options and engineering support available, the ATF Xtend™ Offline is engineered to cater to the specific needs of pharmaceutical manufacturers, R&D labs, and biotech firms.
Benefits
- Enhances laboratory productivity by allowing uninterrupted, unattended operation.
- Ensures consistent and reliable results with automated, repeatable testing processes.
- Minimizes maintenance efforts and downtime with a self-cleaning system.
- Meets stringent compliance requirements, ensuring alignment with industry standards.
- Safeguards data integrity through robust, 21 CFR part 11-compliant data management.
- Applications
- Medical devices,Gels,Pellets,Granules,Microspheres,Catalysts,Stents,Food,Nano suspensions,Fine chemicals,Coated lenses,Soft-gelatin capsules,Implants,Animal health,Capsules,Powders,Washtabs,Transdermal patches,Creams,Suppositories,Semi-solids,Apis,Tablets,Injectable suspensions
- End products
- Fish oil soft-gelatin capsules,Vitamin d capsules,Dental implants,Omega-3 supplements for animal health,Anti-aging face creams,Pharmaceutical catalysts,Nicotine transdermal patches,Injectable insulin suspensions,Antifungal gels,Paracetamol suppositories,Dishwasher tablets,Paracetamol tablets,Scratch-resistant coated lenses,Drug-eluting stents
- Steps before
- Media Preparation,Heating,Degassing
- Steps after
- Sampling,Filtration,Cleaning,Gravimetric Verification
- Input ingredients
- dissolution media,tablets,capsules,pellets,API's,powders,granules,soft-gelatin capsules,suppositories,medical devices,stents,microspheres,nano suspensions,injectable suspensions,semi-solids,gels,creams,transdermal patches,washtabs,fine chemicals,catalysts,food,animal health products
- Output ingredients
- dissolution samples,filtered samples,collected samples,capped LC vials,wellplates,test tubes,HPLC analysis,UPLC analysis
- Automation
- Fully automated
- Self-Cleaning
- Yes
- Filtration Precision
- 0.2 microns
- Sample Collection
- Up to 60 timepoints
- Media Preparation
- Automatic heat and degas,pH change
- Vessel Volume Verification
- Gravimetric
- Data Compliance
- 21 CFR part 11
- Compliance
- USP,Ph.Eur.
- Cooling
- Flow-through rack cooling
- Degassing Method
- Helium sparging/vacuum
- Automation level
- Fully Automated
- Batch vs. continuous operation
- Batch
- CIP/SIP
- Self-cleaning
- Cleaning method
- Automated Vessel Cleaning
- Traceability
- Automatic Execution and Recording
- Repeatability
- High Precision
- Sample Collection
- Automated up to 60 timepoints
- Cleanability
- Self-cleaning
- Density/particle size
- 0.5–2.5 g/cm³ / 50–1000 µm
- USP Compliance
- USP 1/2/4/5/6
- Machine footprint
- Compact
- Control panel type
- HMI with touchscreen interface
- Sample collection format
- Test tubes,capped vials,or wellplates
- Compliance software
- q-doc® software with 21 CFR part 11 compliance
- Video monitoring
- CenterView™
- Robotic automation
- RS robotic station for basket exchange and sinker retrieval
- System modules
- Integrated MP-F,CP-F,FS-F,CS-F modules
- Market info
- Sotax AG is renowned for its expertise in manufacturing high-quality pharmaceutical testing equipment, including dissolution testing systems, and has a strong reputation for reliability, precision, and innovation in laboratory and industrial applications.