Solid target processing system for radionuclide production

Effectively produce a wide range of medical isotopes with precision through an integrated system that automates irradiation to purification processes, ensuring safe and consistent radionuclide synthesis for nuclear medicine applications.

The ALCEO Solid Target Processing System from Comecer is engineered to streamline the production of isotopes for radiopharmaceutical applications. With a fully automated operation, it eliminates manual intervention in the processing sequence, ensuring consistent precision. The system includes modular components like metal and halogen isotope production units, integrated with a pneumatic transfer system and independent cooling mechanisms. It’s designed to produce a range of radioisotopes such as ^61Cu, ^64Cu, and ^124I, critical for nuclear medicine and research. This system can be customized to fit specific isotopic production needs, offering versatile operational modules. It integrates seamlessly with existing cyclotron systems and adheres to stringent GMP standards, ensuring high-purity outputs while maintaining operator safety through minimized radiation exposure. The system also includes advanced purification modules and features corrosion-resistant materials, making it suitable for intensive industrial use.

Benefits

  • Enhances production efficiency by fully automating the radionuclide processing workflow.
  • Increases operator safety through minimized direct handling and exposure to radioactive materials.
  • Reduces operational costs with modular design allowing for tailored configurations and optimized resource use.
  • Ensures high-purity isotope output, compliant with GMP standards for medical applications.
  • Facilitates integration with existing infrastructure, minimizing setup disruption and enhancing system compatibility.

General


Applications
Radiopharmaceutical synthesis,Medical isotopes,Radioisotopes,Radiopharmaceuticals,Radionuclides production,Nuclear medicine
End products
^44sc,^86y,^64cu,^45ti,^61cu,^123i,^68ga,^124i,^89zr
Steps before
Irradiation,Plating,External Plating,Powder Compressing
Steps after
Dissolution,Purification,Evaporation,Storage
Input ingredients
Nickel/Zinc galvanic deposit,Tellurium oxide deposit,Calcium/Strontium carbonate powder
Output ingredients
61Cu,64Cu,89Zr,124I,123I,68Ga,44Sc,86Y,45Ti
Market info
Comecer is known for manufacturing advanced containment and isolation systems, particularly in the pharmaceutical and nuclear medicine sectors, with expertise in custom-engineered equipment, ensuring high safety and compliance standards.

Technical Specifications


Automation
Fully automated
Isotope production
611Cu,64Cu,89Zr,124I,123I,68Ga,44Sc,86Y,45Ti
Pneumatic Target Transfer
Bi-directional between cyclotron and hot cells
Cooling System
Independent water and helium cooling
Target exchange system
Single PTS
Energy range compatibility
5-30 MeV
Halogen System
123I,124I production
Metal System
68Ga,61Cu,64Cu,89Zr,44Sc,45Ti,86Y production
Radiopharma Purification Module
Ion Chromatography
Iodine Evaporation Purification unit
Available
Cooling option
Water-cooled Hexagonal Grid
Process Configuration
Mixed/Separated

Operating Characteristics


Automation level
Fully automated
Batch vs. continuous operation
Mixed or Separated processes
Automation in Target Transfer
Bi-directional Pneumatic Target Transfer
Contamination control
Disposable cassette use
Cooling System
Independent Water and Helium Cooling

Material Compatibility


Biological compatibility
Yes
Cleanability
High
Corrosive resistance (e.g. acids)
Yes

Physical Characteristics


Component integration
Integrated cooling and degrader foil
Target transport system
Pneumatic Transfer System (PTS)
Irradiation unit
Connected to cyclotron
Cooling system
Water and helium cooling
Target positioning
Fully automated

Custom Options


Modular Design
Yes
System Configuration
Mixed/Separated Process
Target Shuttle Type
Metal/Halogen
Irradiation Unit Type
Connected to Cyclotron
Cooling System
Water and Helium
Production Processes
Automatic
Transfer,Storage Module
Pneumatic System
Purification Module
Disposable Cassette
Degrader Foil Integration
Shuttle-Based
External Plating
Nickel/Zinc Electro-deposition
Powder Compressing Station
Calcium/Strontium Pellet